A new cembrane-type diterpenoid from Bornean liverwort Chandonanthus hirtellus.
نویسندگان
چکیده
A new compound, chandonanol (1), along with four known compounds, chandonanthone (2), iso-chandonanthone (3), anastreptene (4), and (6R,7S)-sesquiphellandrene (5), was isolated from the MeOH extract of Bornean liverwort Chandonanthus hirtellus. The structure of the new metabolite was established by analyses of the spectroscopic data (1D NMR, 2D NMR, HRESIMS, and IR). These compounds were tested for their activity against antibiotic-resistant clinical strains. Chandonanol (1) exhibited potent bactericidal activity against Staphylococcus aureus and Escherichia coli.
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ورودعنوان ژورنال:
- Journal of Asian natural products research
دوره 18 7 شماره
صفحات -
تاریخ انتشار 2016